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(1-Hydroxyethylene)diphosphonic acid
CAS number: 2809-21-4
ASK FOR QUOTATIONGroups: Pharmaceutical, Fine & Specialty Chemicals, Oilfield / Mining Chemicals, Water Treatment Chemicals, All Chemicals Information: IUPAC Name: (1-hydroxy-1-phosphono-ethyl)phosphonic acid CAS Number: 2809-21-4 Chemical Formula: C2H8O7P2 Synonyms: (1-Hydroxyethylene) Diphosphonic Acid (1-Hydroxyethylidene) bis(phosphonic acid) (1-Hydroxyethylidene) bisphosphonic acid (1-Hydroxyethylidene) diphoshonic acid (1-Hydroxyethylidene) diphosphonic acid (Hydroxyethylidene) diphosphonic acid 1,1,1-Ethanetriol diphosphonate 1-HYDROXY-1,1-DIPHOSPHONOETHANE 1-Hydroxyethane-1, 1-bisphosphonic acid 1-Hydroxyethane-1,1-bisphosphonic acid 1-Hydroxyethane-1,1-diphosphonate 1-Hydroxyethane-1,1-diphosphonic acid 1-Hydroxyethanediphosphonic acid 1-Hydroxyethylidene-1, 1-diphosphonic acid 1-Hydroxyethylidene-1,1-biphosphonate 1-Hydroxyethylidene-1,1-bisphosphonate 1-Hydroxyethylidene-1,1-diphosphonic acid 1000SL Acetodiphosphonic acid Acide etidronique [INN-French] Acido etidronico [INN-Spanish] Acidum etidronicum [INN-Latin] C07736 D02373 Dequest 2010 Dequest 2015 Dequest Z 010 Diphosphonate (base) EHDP Ethane-1-hydroxy-1, 1-diphosphonate Ethane-1-hydroxy-1,1-bisphosphonate Ethane-1-hydroxy-1,1-diphosphonate Ethane-1-hydroxy-1,1-diphosphonic acid Etidronic acid (USAN) Etidronic acid [USAN:BAN:INN] Ferrofos 510 HEDP Hydroxyethane-1,1-diphosphonic acid Hydroxyethanediphosphonic acid Oxyethylidenediphosphonic acid Phosphonic acid, (1-hydroxyethylidene) bis- Phosphonic acid, (1-hydroxyethylidene) di- Phosphonic acid, 1-hydroxy-1,1-ethanediyl ester RP 61 Turpinal SL Product Info: Phosphonates derived from phosphorous (phosphonic) acid are employed in the applications of scale Inhibition, sequestration, dispersion and corrosion inhibition in addition to the main applications of agricultural chemicals such as fertilizers, pesticides, and soil conditioners. Phosphonates offer a wide range of sequestrants to control metal ions in aqueous systems. By forming stable water soluble complexes with multivalent metal ions, phosphonates prevent undesired interaction by blocking normal reactivity of metal ions. This ability contributes to function as threshold industrial water treatment and metal treatment processes (antiscalants, corrosion inhibitors, chelants, sludge conditioners, pulp bleachings, deflocculants, dispersants, metal cleaners, electroplating and crystal growth modifiers). Phosphonates are also used in manufacturing detergents, cosmetics and personal care products for special functions such as low levels iron control, stain removal, bleach stabilization, peroxide stabilization and anti-encrustation. Phosphonates existing in various compounds as acids or salts are marketed in the form of concentrated solutions. Biphosphonate, a salt, ester, or anion of a dimer of phosphonic acid (diphosphonic acid), inhibits bone resorption as a sodium salt and complexed with technetium Tc 99m for bone imaging. The monophosphonates are not active. Biphosphonates are used in disorders affecting the skeleton such as osteoporosis, metastatic disease, and Paget's disease. While bisphosphonates are analogues of endogenous pyrophosphate structurally, they are characterized by a P-C-P bond, the linking oxygen is replaced with a carbon, which is resistant to enzymatic and chemical hydrolysis. General structure is Bisphosphonate Side chains are responsible for chemical-physicla properties, mechanism of resorption, and pharmacokinetics. It is known that biphosphonates bind strongly to hydroxyapatite crystals at the sites of increased bone turnover preferentially and inhibit the formation, aggregation, and dissolution of the crystals.They also may inhibit osteoclast function directly, promotion of osteoclast apoptosis, and interference with osteoblast-mediated osteoclast activation.
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